Mesudiye village lies on the north-western edge of the Karaman plain, in a continental-climate zone at 1,022 metres above sea level.
Summers are hot and dry, winters cold and snowy; the annual rainfall concentrates in spring and autumn.
The village has 90,485 decares of farmland; the main crops are wheat, barley, sugar beet, maize and sunflower. On the livestock side, as of 2025 the village holds
415 cattle, 2,754 sheep and 817 goats.
The Mesudiye Irrigation Cooperative, founded in 1973, is the foundation of the region's organised water system.
The drip irrigation that arrived in the early 2000s under the leadership of Sezgin Özşahines
significantly raised maize and sunflower yields, especially during the July–August drought.